The use of flumazenil after midazolam-induced conscious sedation
نویسندگان
چکیده
منابع مشابه
Midazolam sedation reversed with flumazenil for cardioversion.
Midazolam was used for anaesthesia in 20 patients undergoing cardioversion; 10 received flumazenil, which caused immediate rapid reversal of anaesthesia, and these patients maintained SpO2 greater than 95%, breathing air, within 5-10 min. In contrast, patients in the placebo group were still partially sedated and required oxygen therapy for up to 2 h to maintain a normal SpO2. Arterial pressure...
متن کاملEffect of flumazenil on midazolam-induced amnesia.
We have studied the effect of i.v. flumazenil 0.01 mg kg-1 on the amnesia and sedation caused by midazolam 2 mg and 5 mg i.v. in volunteers in order to determine the relationship between the actions of the antagonist on these two effects. Midazolam caused dose-dependent central neural depression as assessed by critical flicker fusion frequency, and dose-dependent amnesia for word cards. In subj...
متن کاملThe use of midazolam and flumazenil for invasive radiographic procedures.
This study has examined the use of flumazenil to improve recovery following sedation with midazolam in elderly patients undergoing invasive radiological procedures. Forty patients received either flumazenil or placebo in a randomized double-blind fashion following midazolam sedation. Nalbuphine 10-15 mg was given for premedication. All but one of the patients in the flumazenil group were fully ...
متن کاملOral midazolam for conscious sedation of children during minor procedures.
OBJECTIVE To compare the safety and efficacy of two doses of oral midazolam, and to assess the drug induced amnesia obtained, when used for conscious sedation of children undergoing minor procedures in the accident and emergency (A&E) setting. METHODS A two stage trial was completed: an initial prospective, double blinded, randomised trial comparing 0.2 mg/kg midazolam suspension with 0.5 mg/...
متن کاملMidazolam and drug-drug interactions in dental conscious sedation.
UNLABELLED Careful prescribing is paramount in clinical practice. Potential drug-drug interactions need to be considered. Midazolam is the drug of choice for the purpose of IV sedation. To ensure safe clinical practice, the patient's current medications need to be recorded. CLINICAL RELEVANCE An update on the drug interactions relating to midazolam are worthy of scrutiny as its use becomes mo...
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ژورنال
عنوان ژورنال: British Dental Journal
سال: 2010
ISSN: 0007-0610,1476-5373
DOI: 10.1038/sj.bdj.2010.1132